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From the Cornerstone blog

Education on psychiatric treatment, ketamine, Spravato, and mental wellness from our clinical team.

41 ArticlesAnd growing
August 10, 2026

Could Omega-3s Help Your Mental Health — and a Whole Lot More? What the Science Says

You might already know fish oil is ‘good for you.’ But the science goes much further than you think.

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June 12, 2026

Is Your Peptide Protocol Draining Your Brain Chemistry? What Biohackers Need to Know About Methylation

The landscape of personal health has shifted dramatically with the rise of direct-to-consumer peptide acquisition.

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April 16, 2026

SAM-e and Depression: What's Changed and What Patients Need to Know Now

General education content on SAM-e and depression treatment.

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March 11, 2026

Why Progesterone and SSRIs Can Both Work Quickly for PMDD, Sleep, and Anxiety

Many people are surprised that two very different treatments can help similar symptoms.

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February 5, 2026

Clearing Up the Confusion: L-Theanine, L-Threonine, and Magnesium L-Threonate in Psychiatric Use

Patients and clinicians alike are often confused by similarly named supplements that sound like they serve the same purpose.

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January 23, 2026

Psychedelic Integration and Grief: Why Healing Is Not Closure, but Continuity

One of the most enduring myths about grief is the belief that it ends in closure.

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January 19, 2026

Antiepileptic Drugs (AEDs), Folate, and Vitamin B12 Deficiency

Long-term use is associated with alterations in folate and vitamin B12 metabolism.

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January 19, 2026

Why Methylated B12 Is Often Paired With L-Methylfolate — Especially With Metformin or AEDs

B12 and folate are partners in one-carbon metabolism, essential for neurotransmitter synthesis.

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January 19, 2026

L-Methylfolate (5-MTHF) for Depression: Who Is Most Likely to Respond?

L-methylfolate is the biologically active form of folate that crosses the blood–brain barrier.

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December 19, 2025

Chaste Tree (Vitex agnus-castus) for PMS/PMDD: What to Know Before You Try It

General education content; not medical advice and does not create a clinician–patient relationship.

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December 16, 2025

Low-Dose Naltrexone (LDN): A Surprisingly Versatile Therapy for Pain, Autoimmunity, Mood, and Chronic Fatigue

General education content; not medical advice and does not create a clinician–patient relationship.

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August 11, 2025

Guide to Ketamine and NAD+: How They Work Together to Protect and Heal Your Brain

A simple guide to understanding how these two treatments team up to block damage and restore energy.

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August 1, 2025

Ketamine and the Kynurenine Pathway: A New Understanding of Depression Treatment

How a breakthrough anesthetic reveals the hidden metabolic roots of mental health challenges.

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July 8, 2025

The Best Magnesium for Sleep, Anxiety, and Mood

General education content; not medical advice and does not create a clinician–patient relationship.

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March 5, 2025

Unlocking the Potential of Glutamate in Depression Treatment

Depression is a complex condition with diverse underlying mechanisms.

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February 7, 2025

Everything You Need to Know About Spravato (Esketamine) for Treatment-Resistant Depression

Spravato targets glutamate differently than traditional antidepressants.

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February 1, 2025

Will Psych Providers Be Replaced by AI?

Artificial Intelligence is transforming industries everywhere, including healthcare and psychiatry.

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January 28, 2025

How ADHD Affects Relationships and What You Can Do About It

Common symptoms like distractibility, forgetfulness, and impulsivity often lead to misunderstandings.

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January 23, 2025

A Comprehensive Guide to the Top SAD Lamps of 2025

Seasonal Affective Disorder affects millions during darker winter months when sunlight is limited.

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January 16, 2025

The Synergistic Role of Serotonergic Medications in Augmenting Spravato and IV Ketamine Treatments

Ketamine-based therapies have revolutionized treatment of treatment-resistant depression.

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January 3, 2025

The Role of Concentration in GAD, MDD, and ADHD: A Shared Symptom Across Diagnoses

Concentration is an essential cognitive function allowing us to focus on tasks.

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August 6, 2024

Preparing for IV Ketamine or Spravato Treatment: A Comprehensive Guide

For individuals with treatment-resistant depression, IV ketamine addresses severe depressive symptoms.

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July 31, 2024

Spravato vs. IV Ketamine: Similarities and Differences in Treating Depression

The landscape of depression treatment has been significantly broadened with ketamine-based therapies.

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July 25, 2024

Exploring TMS: A Breakthrough for Patients with Treatment-Resistant Depression and OCD

In the landscape of mental health treatment, medication has long been the primary approach.

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July 8, 2024

Prominent Advocates for Ketamine in Mental Health Treatment

As understanding of mental health evolves, exploration of innovative treatments expands.

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May 10, 2024

IV Ketamine/NAD+ Combination Therapy: Exploring the Potential Synergy Between NAD+ and Ketamine in Treating Depression

Researchers delve into potential synergy between Nicotinamide Adenine Dinucleotide and Ketamine.

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August 7, 2023

Unlocking the Potential: How IV Infusions Can Improve Your Life

Is there a way to optimize your physical and mental health naturally and holistically?

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August 7, 2023

Medication Management for Seniors: Challenges and Solutions

Medication management poses several challenges for seniors living with mental health issues.

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April 7, 2023

Ketamine-Assisted Psychotherapy Is a New and Innovative Way to Treat Mental Healing

Are you struggling with mental health issues or feeling traditional treatments have been ineffective?

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February 24, 2023

What Is the Number One Rule to Losing Weight?

A look at sustainable habits for weight management.

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January 13, 2023

What's the Difference Between Telepsychiatry and Telehealth?

Telepsychiatry is a subset of telehealth using technology like phone and video conferencing.

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January 3, 2023

How Early Childhood Experiences Can Impact Mental Health Later in Life

We all want our children to have happy and healthy lives, but sometimes life doesn't go as planned.

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November 17, 2022

Bipolar Disorder vs. Depression: What's the Difference?

It can be difficult to differentiate between bipolar disorder and depression.

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November 1, 2022

The Surprising Success of Ketamine Treatments for Bi-Polar Depression

Depression is a severe mental health condition affecting millions annually in the United States.

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August 3, 2022

The Diet-Gut-Brain Axis

Although psychiatric disorders are primarily considered brain diseases, the digestive system influences brain health.

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July 21, 2022

A Technical Primer on Over-the-Counter Pregnenolone vs. Prescription Allopregnanolone

General education content; not medical advice and does not create a clinician–patient relationship.

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October 22, 2021

Patience, Coffee, and Gracefulness

The office has an awesome coffee pot; once described, your opinion of it may differ.

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October 12, 2021

Coping With Anxiety and Depression

You've heard the saying before: when life gives you lemons, make lemonade.

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February 21, 2021

Patient Perspective: “The Tears Would Just Come”

Uncontrollable crying for no reason was my sign to finally admit I needed help.

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June 9, 2020

Ketamine: Taking the Obsessions Out of Obsessive-Compulsive Disorder

Obsessive compulsive disorder has been subject to frequent indiscriminate use outside mental health.

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June 8, 2020

Depression and Sleep Problems

Major Depression is one of the most common mental health disorders.

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